Making a perfect page layout is a nice thing to do, It is even nicer if you can make a very neat page layout using minimal graphics and much text, Not surprisingly when it comes to search engines, making the perfect layout is not really important, but making a bad one could severely harm your ranking.

So when designing the layout for your pages you should follow a few guidelines here, First of all make the navigation easy, A navigation that helps the user get quickly from one place to the other is also good enough for the search engine

People are usually looking for either some specific thing or looking for a subject to read more on, so it is best to have things categorized to serve both purposes at the same time, it should be clear to the user where he should be looking for the information he wants and the categories should resemble one topic the user is probably looking to learn more about.